The effects of breathing and coughing exercises on respiratory parameters in COVID-19 patients

Authors

DOI:

https://doi.org/10.15584/ejcem.2026.1.12

Keywords:

cough exercise, COVID-19, deep breathing, nursing care, pneumonia, Triflow

Abstract

Introduction and aim. COVID-19 primarily affects the respiratory system, often resulting in pneumonia and dyspnea that may persist after recovery. This study aimed to evaluate the effect of deep breathing and coughing exercises using a Triflow device on respiratory parameters in patients with COVID-19 pneumonia.

Material and methods. This single-blinded randomized controlled study was conducted with 326 patients diagnosed with COVID-19 pneumonia. Participants were randomly assigned to an experimental group (n=163) or a control group (n=163). The experimental group performed exercises for 10 consecutive days. The control group received routine hospital care, which included routine nurse-led monitoring of vital signs, peripheral oxygen saturation (SpO₂) assessment, medical treatment per clinical guidelines, and supportive care, but no structured breathing-exercise education. Data were analyzed using descriptive statistics, ANOVA, chi-square, and post hoc tests.

Results. After 10 days of intervention, Dyspnea-12 scores decreased more markedly in the experimental group than in the control group (mean change −15 vs. −8 points; p<0.001). Arterial oxygen and SpO₂ levels also improved significantly in the experimental group compared to controls (p<0.001), while respiratory rate decreased to a greater extent (p<0.001). No adverse effects were observed.

Conclusion. Deep breathing and coughing exercises with the Trilow device significantly reduced the severity of dyspnea and improved oxygenation in COVID-19 pneumonia patients. These findings suggest that incorporating structured respiratory exercises into standard care may enhance clinical outcomes and support recovery in this population.

Supporting Agencies

This study was funded by a grant from the Bartin University Scientific Research Projects Unit (Grant No: 2021-FEN-A-016).

Downloads

Download data is not yet available.

References

Special Expert Group for Control of the Epidemic of Novel Coronavirus Pneumonia of the Chinese Preventive Medicine Association. An update on the epidemiological characteristics of novel coronavirus pneumonia (COVID-19). Zhonghua Liu Xing Bing Xue Za Zhi. 2020;41(2):139-144. doi:10.3760/cma.j.issn.0254-6450.2020.02.002

Li Q, Guan X, Wu P, et al. Early transmission dynamics in Wuhan, China, of novel coronavirus-infected pneumonia. N Engl J Med. 2020;382(13):1199-1207. doi:10.1056/NEJMoa2001316

Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395(10223):497-506. doi:10.1016/S0140-6736(20)30183-5

Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020;323(11):1061-1069. doi:10.1001/jama.2020.1585

Prabawa IMY, Silakarma D, Manuaba IBAP, Widnyana M, Jeviana A. Chest therapy and breathing exercise in COVID-19 patient: A case report. Bali Medical Journal. 2021;10(2):495-498. doi:10.15562/bmj.v10i2.2403

Guan WJ, Ni ZY, Hu Y, et al. Clinical characteristics of 2019 novel coronavirus infection in China. medRxiv. 2020;1-30. doi:10.1101/2020.02.06.20020974

Gonzalez-Gerez JJ, Bernal-Utrera C, Anarte-Lazo E, Garcia-Vidal JA, Botella-Rico JM, Rodriguez-Blanco C. Therapeutic pulmonary telerehabilitation protocol for patients affected by COVID-19, confined to their homes: study protocol for a randomized controlled trial. Trials. 2020;21(1). doi:10.1186/s13063-020-04494-w

Lewis LK, Williams MT, Olds TS. The active cycle of breathing technique: A systematic review and meta-analysis. Respir Med. 2012;106(2):155-172. doi:10.1016/J.RMED.2011.10.014

Felten-Barentsz KM, van Oorsouw R, Klooster E, et al. Recommendations for hospital-based physical therapists managing patients with COVID-19. Phys Ther. 2020;100(9):1444-1457. doi:10.1093/ptj/pzaa114

Polastri M. Physiotherapy in hospitalised patients with COVID-19 Disease: what we know so far. Int J Ther Rehabil. 2020;27(3). doi:10.12968/ijtr.2020.0035

Sheikh S, Rostami A, Shahbazi A, et al. Clinical effectiveness of guided breathing exercises in reducing anxiety, stress, and depression in COVID-19 patients. Sci Rep. 2024;14(1):1-10. doi:10.1038/s41598-024-78162-3

Frutos-Reoyo EJ, Cantalapiedra-Puentes E, González-Rebollo AM. Rehabilitación domiciliaria en el paciente con COVID-19. Rehabilitacion. 2020;55(2):83. doi:10.1016/J.RH.2020.10.004

Sümbüloğlu K, Sümbüloğlu V. Biostatistics. 17th ed. Edited by Hatipoğlu T. Ankara: Hatiboğlu Yayınevi; 2016.

Yorke J, Moosavi SH, Shuldham C, Jones PW. Quantification of dyspnoea using descriptors: development and initial testing of the dyspnoea-12. Thorax. 2010;65(1):21. doi:10.1136/THX.2009.118521

Gök Metin Z, Helvacı A. Dispne-12 ölçeğinin Türkçe geçerlik ve güvenirlik çalışması. Hacettepe Univ Hemşirelik Fakültesi Derg. 2018;5(2):102-115. doi:10.31125/hunhemsire.454354

T.C. Ministry of Health. COVID-19 Adult treatment algorithm. Accessed May 6, 2025. https://covid19.saglik.gov.tr/TR-66328/eriskin-tedavi-algoritmasi.html.

Kader M, Hossain MA, Reddy V, Perera NKP, Rashid M. Effects of short-term breathing exercises on respiratory recovery in patients with COVID-19: A quasi-experimental study. BMC Sports Sci Med Rehabil. 2022;14(1):1-10. doi:10.1186/s13102-022-00451-z

Öner Cengiz H, Ayhan M, Güner R. Effect of deep breathing exercise with Triflo on dyspnoea, anxiety and quality of life in patients receiving COVID-19 treatment: A randomized controlled trial. J Clin Nurs. 2021;31(23):3439-3453. doi:10.1111/jocn.16171

Allali G, Marti C, Grosgurin O, Morélot-Panzini C, Similowski T, Adler D. Dyspnea: the vanished warning symptom of COVID-19 pneumonia. J Med Virol. 2020;92(11):2272-2273. doi:10.1002/jmv.26172

Zha L, Xu X, Wang D, Qiao G, Zhuang W, Huang S. Modified rehabilitation exercises for mild cases of COVID-19. Ann Cardiothorac Surg. 2020;9(5):3100-3106. doi:10.21037/apm-20-753

Abdullahi A. Safety and efficacy of chest physiotherapy in patients with COVID-19: A critical review. Front Med. 2020;7:1-6. doi:10.3389/fmed.2020.00454

Khan MA, Khan ZA, Charles M, et al. Cytokine storm and mucus hypersecretion in COVID-19: review of mechanisms. J Inflamm Res. 2021;14:175-189. doi:10.2147/JIR.S271292

Kumar SS, Binu A, Devan Aswathy R, Nath Lekshmi R. Mucus targeting as a plausible approach to improve lung function in COVID-19 patients. Med Hypotheses. 2021;156(110680):1-9. doi:10.1016/j.mehy.2021.110680

Mollerup A, Henriksen M, Larsen SC, et al. Effect of PEP flute self-care versus usual care in early COVID-19: non-drug, open-label, randomised controlled trial in a Danish community setting. BMJ. 2021;375:e066952. doi:10.1136/bmj-2021-066952

Li K, Wu J, Wu F, et al. The clinical and chest CT features associated with severe and critical COVID-19 pneumonia. Invest Radiol. 2020;55(6):327-331. doi: 10.1097/RLI.0000000000000672

Li X, Ma X. Acute respiratory failure in COVID-19: Is tt "Typical" ARDS? Crit Care. 2020;24(1):1-5. doi:10.1186/s13054-020-02911-9

Nouri-Vaskeh M, Sharifi A, Khalili N, Zand R, Sharifi A. Dyspneic and non-dyspneic (silent) hypoxemia in COVID-19: possible neurological mechanism. Clin Neurol Neurosurg. 2020;198:106217. doi:10.1016/j.clineuro.2020.106217

Pan F, Yang L, Li Y, et al. Factors associated with death outcome in patients with severe coronavirus disease-19 (COVID-19): A case-control study. Int J Med Sci. 2020;17(9):1281-1292. doi:10.7150/ijms.46614

Zheng QN, Xu MY, Zheng Y Le, Wang XY, Zhao H. Prediction of the rehabilitation duration and risk management for mild-moderate COVID-19. Disaster Med Public Health Prep. 2020;14(5):652-657. doi:10.1017/DMP.2020.214

Downloads

Published

2025-11-25

How to Cite

Uçar, Özge, Çelik, S., Uzun, S., Karahan, E., & Altıntaş, S. (2025). The effects of breathing and coughing exercises on respiratory parameters in COVID-19 patients. European Journal of Clinical and Experimental Medicine. https://doi.org/10.15584/ejcem.2026.1.12

Issue

Section

ORIGINAL PAPERS