Effects of obesity on health condition with an emphasis on bone tissues disorders

Authors

  • Dariusz Wolski Department of Animal Anatomy and Histology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Lublin, Poland; Department of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Lublin, Poland https://orcid.org/0000-0001-6563-0247
  • Joanna Michalik Department of Oncology and Environmental Health, Faculty of Nursing and Health Sciences, Medical University of Lublin, Lublin, Poland https://orcid.org/0000-0002-3432-9125
  • Marek Bieńko Department of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Lublin, Poland https://orcid.org/0000-0002-9706-6676
  • Radosław P. Radzki Department of Animal Physiology, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, Lublin, Poland https://orcid.org/0000-0002-5439-2420

DOI:

https://doi.org/10.15584/ejcem.2018.2.6

Keywords:

fat tissue, bone, obesity, osteosarcopenic obesity, osteoporosis

Abstract

Introduction. Obesity is today one of the most dangerous and the fastest growing civilization diseases in the world. The number of overweight or obese people is continually increasing. Obesity is defined as abnormal fat accumulation in an organism that may cause health impairment. Obesity may be conducive to an increased risk increase for occurrence of cardiovascular diseases as well as stroke, some types of cancer, endocrinal disorders, osteoarthritis and other bone disorders. Some studies have demonstrated that high body mass index (BMI) is protective against the development of osteoporosis and osteoporotic fractures in men and women. In slim people with a lower BMI than normal, weight loss is associated with low bone mineral density (BMD). On the other hand, obesity in childhood may lead to fragility fractures and may lead to early development of osteoporosis in adulthood. Currently, we have numerous methods for measurement of obesity such as dual-energy X-ray absorptiometry (DXA), bioelectrical impedance analysis (BIA), total body electrical conductivity (TOBEC) as well as magnetic resonance imaging (MRI) and computed tomography (CT). These methods are useful for diagnosing obesity and bone tissue disorders such as osteopenia with sarcopenia or osteoporosis, in particular in perimenopausal women and men after andropause.

Aim. The purpose of the study was review the literature on obesity and bone tissue disorders and their interrelations.

Material and method. Analysis of literature.

Downloads

Download data is not yet available.

References

Risk Factors of obesity. World Health Organization Website. http://www.who.int/gho/ncd/risk_factors/obesity_text/en/. Accessed March 10, 2018.

Risk Factors of overweight. World Health Organization Website. http://www.who.int/gho/ncd/risk_factors/overweight_text/en/. Accessed March 12, 2018.

Child growth standards. World Health Organization Website. http://www.who.int/childgrowth/publications/physical_status/en/ Accessed March 12, 2018.

Hutley L, Prins JB. Fat as an endocrine organ: Relationship to the metabolic syndrome. Am J Med Sci. 2005;330:280-289.

Tatoń J, Czech A, Bernas M. Otyłość- zespół metaboliczny. Warszawa: PZWL;2007:5-23.

Skowrońska B, Fichna M, Fichna P. Rola tkanki tłuszczowej w układzie dokrewnym. Endokrynologia, Otyłość i Zaburzenia Przemiany Materii. 2005;1(3):21-29.

Bieńko M, Lis A, Wolski D, et al. Relationship between fat tissue and bone tissue. Med Weter. 2016;72(4):217-221.

Siemińska L. Adipose tissue. Pathophysiology, distribution, sex differences and the role in inflammation and cancerogenesis. Endokrynol Pol. 2007;4:42-50.

Fields DA, Goran MI. Body composition techniques and the four-compartment model in children. J Appl Physiol. 2000;89:613–620.

Loan V, Mayclin PL. Body composition assessment: dual-energy x-ray absorptiometry (DEXA) compared to reference methods. Eur J Clin Nutr. 1992;46:125–130.

Wong WW, Hergenroeder AC, Stuff JE et al. Evaluating body fat in girls and female adolescents: advantages and disadvantages of dual-energy x‐ray absorptiometry. Am J Clin Nutr. 2002;76:384–389.

Tyrell VJ, Richards G, Hofman P, Gillies GF, Robinson E, Cutfield, WS. Foot‐foot bio‐electrical impedance analysis: a valuable tool for the measurement of body composition in children. Int J Obes Relat Metab Disord. 2001;25:273–278.

Reilly JJ, Wilson J, Carmichael J M, McColl JH, Durnin JVGA. Ability of bioelectric impedance to predict fat-free mass in pre‐pubertal children. Pediatr Res. 1996;39:176–179.

Widhalm K, Schonegger K, Huemer C, Auterith A. Does the BMI reflect body fat in obese children and adolescents? A study using the TOBEC method. International Journal of Obesity. 2001;25,279-285.

Goran MI, Kaskoun MC, Shuman WP. Intra-abdominal adipose tissue in young children. Int J Obes. 1995;19:279–283.

Fox K, Peters D, Armstrong N, Sharpe P, Bell M. Abdominal fat deposition in 11-year-old children. Int J Obes. 1993;17:11–16.

de Ridder CM, de Boer RW, Seidell JC, et al. Body fat distribution in pubertal girls quantified by magnetic resonance imaging. Int J Obes.1992;16:443–449.

Fantuzzi G: Adipose tissue, adipokines, and inflammation. American Academy of Allergy, Asthma, and Immunology. 2005;5:911-919.

Cao JJ. Effects of obesity on bone metabolism. Journal of Orthopaedic Surgery and Research. 2011;6(30):1-7.

Kershaw EE, Flier JS. Adipose tissue as an endocrine organ. J Clin Endocrinol Metabol. 2010;4(89):2548-2556.

Greco EA, Fornari R, Rossi F, et al. Is obesity protective for osteoporosis? Evaluation of bone mineral density in individuals with high body mass index. Int J Clin Pract. 2010;64(6):817-20.

Villareal DT, Fontana L, Weiss EP, et al. Bone mineral density response to caloric restriction-induced weight loss or exercise-induced weight loss: a randomized controlled trial. Arch Intern Med. 2006;166:2502-2510.

Shapses SA, Sukumar D. Bone metabolism in obesity and weight loss. Annu Rev Nutr. 2012;32:287-309.

Ormsbee MJ, Prado CM, Ilich JZ, et al. Osteosarcopenic obesity: the role of bone, muscle, and fat on health. J Cachexia Sarcopenia Muscle. 2014;5(3):183-192.

Shin H, Liu PY, Panton L, et al. Physical performance in relation to body composition and bone mineral density in healthy, overweight, and obese postmenopausal women. J Geriatr Phys Ther. 2014;37(1):7-16.

Liu PY, Ilich JZ, Brummel-Smith K, et al. New insight into fat, muscle and bone relationship in women: determining the threshold at which body fat assumes negative relationship with bone mineral density. Int J Prev Med. 2014;5(11):1452-1463.

Ilich-Ernst J, Brownbill RA, Ludemann MA, et al. Critical factors for bone health in women across the age span: how important is muscle mass? Medscape Women's Health. 2002;7(3):2-8.

Zhao LJ, Jiang H, Papasian CJ, et al. Correlation of obesity and osteoporosis: effect of fat mass on the determination of osteoporosis. J Bone Miner Res. 2008;23(1):17-29.

Felson DT, Zhang Y, Hannan MT, et al. Effects of weight and body mass index on bone mineral density in men and women: the Framingham study. J Bone Miner Res. 1993;8(5):567-573.

Ravn P, Cizza G, Bjarnason NH, et al. Low body mass index is an important risk factor for low bone mass and increased bone loss in early postmenopausal women. Early Postmenopausal Intervention Cohort (EPIC) study group. J Bone Miner Res. 1999;14(9):1622-1627.

Lau EM, Chan YH, Chan M, et al. Vertebral deformity in Chinese men: prevalence, risk factors, bone mineral density, and body composition measurements. Calcif Tissue Int. 2000;66:47-52.

Christensen P, Riecke BF, Bliddal H, et al. Improved nutritional status and bone health after diet-induced weight loss in sedentary osteoarthritis patients: a prospective cohort study. Europ J Clinic Nutri. 2012;66:504–509.

Gimble JM, Zvonic S, Floyd ZE, et al. Playing with bone and fat. J Cell Biochem. 2006;98:251-266.

Sornay-Rendu E, Boutroy S, Vilayphiou N, et al. In obese postmenopausal women, bone microarchitecture and strength are not commensurate to greater body weight: the Os des Femmes de Lyon (OFELY) study. J Bone Miner Res. 2013;28(7):1679-1687.

Sowers MF, Kshirsagar A, Crutchfield MM, et al. Joint influence of fat and lean body composition compartments on femoral bone mineral density in premenopausal women. Am J Epidemiol. 1992;136:257-265.

Salamone LM, Glynn N, Black D, et al. Body composition and bone mineral density in premenopausal and early perimenopausal women. J Bone Miner Res. 1995;10:1762-1768.

Lenchik L, Register TC, Hsu FC, et al. Adiponectin as a novel determinant of bone mineral density and visceral fat. Bone 2003;33:646-651.

Downloads

Published

2018-06-30

How to Cite

Wolski, D., Michalik, J., Bieńko, M., & Radzki, R. P. (2018). Effects of obesity on health condition with an emphasis on bone tissues disorders. European Journal of Clinical and Experimental Medicine, 16(2), 117–122. https://doi.org/10.15584/ejcem.2018.2.6

Issue

Section

REVIEW PAPERS

Most read articles by the same author(s)