Social vulnerability and medication adherence in individuals with chronic obstructive pulmonary disease
DOI:
https://doi.org/10.15584/ejcem.2024.4.13Keywords:
chronic obstructive pulmonary disease, frailty, medication adherence, social vulnerabilityAbstract
Introduction and aim. The association between social vulnerability and medication adherence in individuals with chronic obstructive pulmonary disease is unclear. The aim of this study was to show the correlation of social vulnerability and medication adherence in individuals with chronic obstructive pulmonary disease.
Material and methods. Data collection was conducted by face to face interview in November 2022 and May 2023. Social vulnerability and medication adherence were evaluated using the Social Vulnerability Scale and the Medication Adherence Report Scale respectively.
Results. The mean scores of individuals with chronic obstructive pulmonary disease for social vulnerability and medication adherence were 20.02±6.69 and 22.76±3.29 respectively. Levels of social vulnerability varied according to comorbidity, hypertension, heart failure, visit to emergency service in the last three months due to COPD exacerbation, and using herbal products instead of medication (p<0.05). Mean scores for medication adherence were lower in women, never smokers, and those who used herbal products instead of medication (p<0.05).
Conclusion. Having a higher level of social vulnerability is associated with worse medication adherence (r=-0.31, p<0.01). Individuals using herbal products are found to be at risk for social vulnerability and non-adherence to medication (p<0.05).
Downloads
References
Global strategy for the diagnosis, management and prevention of COPD, Global Initiative for Chronic Obstructive Lung Disease (GOLD), 2022. https://goldcopd.org/wp-content/uploads/2021/12/GOLD-REPORT-2022-v1.1-22Nov2021_WMV.pdf. Accessed May 13, 2023.
Dunn B. Updated guidelines for chronic obstructive pulmonary disease. JAAPA. 2019;32(1):49-51. doi: 10.1097/01.JAA.0000550297.68348.78
Singh D. Small airway disease in patients with chronic obstructive pulmonary disease. Tuberc Respir Dis. 2017;80(4):317-324. doi: 10.4046/trd.2017.0080
Świątoniowska N, Chabowski M, Polański J, Mazur G, Jankowska-Polańska B. Adherence to therapy in Chronic Obstructive Pulmonary Disease: A Systematic Review. Adv Exp Med Biol. 2020;1271:37-47. doi: 10.1007/5584_2019_477
O'Toole J, Krishnan M, Riekert K, Eakin MN. Understanding barriers to and strategies for medication adherence in COPD: A qualitative study. BMC Pulm Med. 2022;22(1):98. doi: 10.1186/s12890-022-01892-5
Brown MT, Bussell J, Dutta S, Davis K, Strong S, Mathew S. Medication adherence: Truth and consequences. Am J Med Sci. 2016;351(4):387-399. doi: 10.1016/j.amjms.2016.01.010
Jarab AS, Mukattash TL. Exploring variables associated with medication non-adherence in patients with COPD. Int J Clin Pharm. 2019;41(5):1202-1209. doi: 10.1007/s11096-019-00895-3
Li H, Chen Y, Zhang Z, Dong X, Zhang G, Zhang H. Handling of diskus dry powder ınhaler in chinese chronic obstructive pulmonary disease patients. J Aerosol Med Pulm Drug Deliv. 2014;27(3):219-227. doi: 10.1089/jamp.2012.1033
Poletti V, Pagnini F, Banfi P, Volpato E. Illness perceptions, cognitions, and beliefs on COPD patients' adherence to treatment: A systematic review. Patient Prefer Adherence. 2023;28(17):1845-1866. doi: 10.2147/PPA.S412136
Moradkhani B, Mollazadeh S, Niloofar P, Bashiri A, Oghazian MB. Association between medication adherence and health-related quality of life in patients with chronic obstructive pulmonary disease. J Pharm Health Care Sci. 2021;7(1):40. doi: 10.1186/s40780-021-00222-x
Chen PJ, Yang KY, Perng WC, Lin KC, Wang KY. Effect of dyspnea on frailty stages and related factors in Taiwanese men with COPD. Int J Chron Obstruct Pulmon Dis. 2018;15(13):2463-2469. doi: 10.2147/COPD.S172694
Kennedy CC, Novotny PJ, LeBrasseur NK, Wise RA, Sciurba FC, Benzo RP. Frailty and clinical outcomes in Chronic Obstructive Pulmonary Disease. Ann Am Thorac Soc. 2019;16(2):217-224. doi: 10.1513/AnnalsATS.201803-175OC
Kusunose M, Oga T, Nakamura S, Hasegawa Y, Nishimura K. Frailty and patient-reported outcomes in subjects with chronic obstructive pulmonary disease: are they independent entities? BMJ Open Respir Res. 2017;3;4(1):e000196. doi: 10.1136/bmjresp-2017-000196
Symvoulakis EK, Kamekis A, Drakonaki E, Mastrodemou S, Ryerson CJ, Antoniou K. Frailty and chronic respiratory disease: the need for a multidisciplinary care model. Sarcoidosis Vasc Diffuse Lung Dis. 2021;38(3):e2021031. doi: 10.36141/svdld.v38i3.11599
Lahousse L, Ziere G, Verlinden VJ, et al. Risk of frailty in elderly with COPD: A population-based study. J Gerontol A Biol Sci Med Sci. 2016;71(5):689-695. doi: 10.1093/gerona/glv154
Singer JP, Diamond JM, Gries CJ, et al. Frailty phenotypes, disability, and outcomes in adult candidates for lung transplantation. Am J Respir Crit Care Med. 2015;192(11):1325-1334. doi: 10.1164/rccm.201506-1150OC
Marengoni A, Vetrano DL, Manes-Gravina E, Bernabei R, Onder G, Palmer K. The relationship between COPD and frailty: A systematic review and meta-analysis of observational studies. Chest. 2018;154(1):21-40. doi: 10.1016/j.chest.2018.02.014
Gephine S, Mucci P, Grosbois JM, Maltais F, Saey D. Physical frailty in COPD patients with chronic respiratory failure. Int J Chron Obstruct Pulmon Dis. 2021;17(16):1381-1392. doi: 10.2147/COPD.S295885
Maddocks M, Kon SS, Canavan JL, et al. Physical frailty and pulmonary rehabilitation in COPD: A prospective cohort study. Thorax. 2016;71(11):988-995. doi: 10.1136/thoraxjnl-2016-208460
Hirai K, Tanaka A, Oda N, et al. Prevalence and impact of social frailty in patients with Chronic Obstructive Pulmonary Disease. Int J Chron Obstruct Pulmon Dis. 2023;5(18):2117-2126. doi: 10.2147/COPD.S418071
Lee YC, Chang KY, Mirsaeidi M. Association of county-degree social vulnerability with chronic respiratory disease mortality in the United States. Ann Am Thorac Soc. 2023;20(1):47-57. doi: 10.1513/AnnalsATS.202202-136OC
Bessa B, Ribeiro O, Coelho T. Assessing the social dimension of frailty in old age: A systematic review. Arch Gerontol Geriatr. 2018;78:101-113. doi: 10.1016/j.archger.2018.06.005
van Oostrom SH, van der A DL, Rietman ML, et al. A four-domain approach of frailty explored in the Doetinchem Cohort Study. BMC Geriatr. 2017;17(1):1-11. doi: 10.1186/s12877-017-0595-0
Sarıçam H. The Turkish version of the Social Vulnerability Scale: The study of validity and reliability. International Online Journal of Educational Sciences. 2015;7(1):190-202. doi: 10.15345/iojes.2015.01.016
Makizako H, Shimada H, Doi T, et al. Social frailty leads to the development of physical frailty among physically non-frail adults: a four-year follow-up longitudinal cohort study. Int J Environ Res Public Health. 2018;15(3):490. doi: 10.3390/ijerph15030490
Guan C, Niu H. Frailty assessment in older adults with chronic obstructive respiratory diseases. Clin Interv Aging. 2018;29(13):1513-1524. doi: 10.2147/CIA.S173239
Makizako H, Shimada H, Tsutsumimoto K, et al. Social frailty in community-dwelling older adults as a risk factor for disability. J Am Med Dir Assoc. 2015;16(11):1003.e7-11. doi: 10.1016/j.jamda.2015.08.023
Limpawattana P, Putraveephong S, Inthasuwan P, Boonsawat W, Theerakulpisut D, Chindaprasirt J. Frailty syndrome in ambulatory patients with COPD. Int. J. Chronic Obstr Pulm Dis. 2017;12:1193-1198. doi: 10.2147/COPD.S134233
Mittal N, Raj R, Islam EA, Nugent K. The frequency of frailty in ambulatory patients with chronic lung diseases. J Prim Care Community Health. 2016;7(1):10-15. doi: 10.1177/2150131915603202
Tsutsumimoto K, Doi T, Makizako H, et al. Association of social frailty with both cognitive and physical deficits among older people. J Am Med Dir Assoc. 2017;18(7):603-607. doi: 10.1016/j.jamda.2017.02.004
Mah JC, Penwarden JL, Pott H, Theou O, Andrew MK. Social vulnerability indices: A scoping review. BMC Public Health. 2023;23(1):1253. doi: 10.1186/s12889-023-16097-6
Muz G, Erat A, Şamdanlı Ş, Yavuzer Bayrak N. Use of integrative medicines by chronic obstructive pulmonary disease patients and its relation with hopelessness levels. Cukurova Med J. 2020;45(4):1598-1606. doi: 10.17826/cumj.742875
Temeloğlu ŞE, Sertel BÖ, Sindel D. The validity and reliability study of the Turkish adaptation of medical adherence report scale. J Ist Faculty Med. 2019;82(1):52-61. doi: 10.26650/IUITFD.413637
Pinsker DM, Stone VE, Pachana NA, Greenspan S. Social vulnerability scale for older adults: A validation study. Clinical Psychologist. 2006;10:117-127. doi: 10.1080/13284200600939918
Horne R, Weinman J. Self-regulation and selfmanagement in asthma: Exploring the role of illness perceptions and treatment beliefs in explaining non-adherence to preventer medication. Psychology & Health. 2002;17(1):17-32. doi: 10.1080/08870440290001502
Turan O, Turan PA, Mirici A. Parameters affecting inhalation therapy adherence in elderly patients with chronic obstructive lung disease and asthma. Geriatr Gerontol Int. 2017;17(6):999-1005. doi: 10.1111/ggi.12823
Vetrano DL, Bianchini E, Onder G, et al. Poor adherence to chronic obstructive pulmonary disease medications in primary care: Role of age, disease burden and polypharmacy. Geriatrics & gerontology international, 2017;17(12):2500-2506. doi: 10.1111/ggi.13115
Humenberger M, Horner A, Labek A, et al. Adherence to inhaled therapy and its impact on chronic obstructive pulmonary disease (COPD). BMC Pulmonary Medicine. 2018;18(1):163. doi: 10.1186/s12890-018-0724-3
Müllerová H, Landis SH, Aisanov Z, et al. Health behaviors and their correlates among participants in the Continuing to Confront COPD International Patient Survey. Int J Chron Obstruct Pulmon Dis. 2016;27(11):881-890. doi: 10.2147/COPD.S102280
Duarte-de-Araújo A, Teixeira P, Hespanhol V, Correia-de-Sousa J. COPD: analyzing factors associated with a successful treatment. Pulmonology. 2019;26(2):66-72. doi: 10.1016/j.pulmoe.2019.05.012
Regmi MR, Tandan N, Parajuli P, et al. Social Vulnerability Indices as a Risk Factor for Heart Failure Readmissions. Clin Med Res. 2021;19(3):116-122. doi: 10.3121/cmr.2021.1603
Wallace LMK, Theou O, Pena F, Rockwood K, Andrew MK. Social vulnerability as a predictor of mortality and disability: Cross-country differences in the survey of health, aging, and retirement in Europe (SHARE) Aging Clin Exp Res. 2015;27:365-372. doi: 10.1007/s40520-014-0271-6
Armstrong JJ, Andrew MK, Mitnitski A, Launer LJ, White LR, Rockwood K. Social vulnerability and survival across levels of frailty in the Honolulu-Asia Aging Study. Age Ageing. 2015;44:709-712. doi: 10.1093/ageing/afv016
Acosta-Benito MA, Sevilla-Machuca I. Using prefrailty to detect early disability. J Family Community Med. 2016;23(3):140-144. doi: 10.4103/2230-8229.189106
Nguyen TN, Ngangue P, Bouhali T, Ryan BL, Stewart M, Fortin M. Social vulnerability in patients with multimorbidity: A cross-sectional analysis. Int J Environ Res Public Health. 2019;16(7):1244. doi: 10.3390/ijerph16071244
Bunt S, Steverink N, Olthof J, Van Der Schans CP, Hobbelen JSM. Social frailty in older adults: a scoping review. Eur J Ageing. 2017;14(3):323-334. doi: 10.1007/s10433-017-0414-7
Kuzulu A, Bilgin G, Arslan İ, et al. Evaluation of social relationships in COPD patients. Ankara Med J. 2017;4:204-215. doi: 10.17098/amj.364158
Chen Z, Fan VS, Belza B, Pike K, Nguyen HQ. Association between social support and self-care behaviors in adults with chronic obstructive pulmonary disease. Ann Am Thorac Soc. 2017;14(9):1419-1427. doi: 10.1513/AnnalsATS.201701-026OC
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 European Journal of Clinical and Experimental Medicine
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our open access policy is in accordance with the Budapest Open Access Initiative (BOAI) definition: this means that articles have free availability on the public Internet, permitting any users to read, download, copy, distribute, print, search, or link to the full texts of these articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose, without financial, legal, or technical barriers other than those inseparable from having access to the Internet itself.
All articles are published with free open access under the CC-BY Creative Commons attribution license (the current version is CC-BY, version 4.0). If you submit your paper for publication by the Eur J Clin Exp Med, you agree to have the CC-BY license applied to your work. Under this Open Access license, you, as the author, agree that anyone may download and read the paper for free. In addition, the article may be reused and quoted provided that the original published version is cited. This facilitates freedom in re-use and also ensures that Eur J Clin Exp Med content can be mined without barriers for the research needs.
