Comparison of novel bioactive, bioceramic materials in vital pulp therapy in deciduous teeth – a clinical in vivo study
DOI:
https://doi.org/10.15584/ejcem.2024.4.22Keywords:
calcium hydroxide, children, deciduous teeth, pulp cappingAbstract
Introduction and aim. The use of modern bioceramic materials has enhanced the predictability of vital pulp therapy. This study aimed to assess the clinical success of Biodentine, modified NeoPutty mineral trioxide aggregate (MTA), and calcium hydroxide Ca(OH)2 as pulp capping materials for indirect pulp capping in carious primary teeth.
Material and methods. Indirect pulp treatment (IPT) was performed on 36 deciduous molars in 36 patients who were presented with deep carious lesions. The teeth were randomly assigned to three groups: Biodentine (12 teeth), modified NeoPuttyMTA (12 teeth), and Ca(OH)2 (12 teeth).
Results. A statistical analysis was conducted using SPSS software version 21.0. Pearson’s Chi-square test was employed to compare success and failure rates among Biodentine, modified Neoputty MTA, and Ca(OH)2 at three different time intervals (30, 90, and 180 days) and overall success and failure rates regardless of the time intervals. In the statistical analysis, different pulp capping materials yielded varying success rates. The modified NeoPutty MTA group demonstrated a success rate of 91.67%, the Biodentine group 83.33%, and the Ca(OH)2 group 58.33% after 6 months. However, these differences were not statistically significant.
Conclusion. IPT with calcium silicate-based materials, such as Biodentine and modified NeoPutty MTA, showed superior results when compared to the use of calcium hydroxide Ca(OH)2. Although differences in success rates were observed among the materials, they did not reach statistical significance.
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References
Schwendicke F, Frencken JE, Bjørndal L, et al. Managing Carious Lesions: Consensus Recommendations on Carious Tissue Removal. Adv Dent Res. 2016;28(2):58-67. doi: 10.1177/0022034516639271
Bjørndal L, Simon S, Tomson PL, Duncan HF. Management of deep caries and the exposed pulp. Int Endod J. 2019;52(7):949-973. doi: 10.1111/iej.13128
Tan SY, Yu VSH, Lim KC, et al. Long-term pulpal and restorative outcomes of pulpotomy in mature permanent teeth. J Endod. 2020;46(3):383-390. doi: 10.1016/j.joen.2019.11.009
Monea M, Mihai P, Stoica A, Teodore S. Histologic evaluation of tertiary dentine after indirect pulp capping procedures. Key Eng Mater. 2016;695:260-263. doi: 10.4028/www.scientific.net/kem.695.260
Seale N, Coll J. Vital pulp therapy for primary dentition. Gen Dent. 2010;58(3):194-200.
Chauhan A, Dua P, Saini S, Mangla R, Butail A, Ahluwalia S. In vivo outcomes of indirect pulp treatment in primary posterior teeth: 6 months' follow-up. Contemp Clin Dent. 2018;9(1). doi: 10.4103/ccd.ccd_48_18.
Julious SA, Zariffa N. The ABC of pharmaceutical trial design: some basic principles. J Pharm Stat. 2002;1:45-53. doi: 10.1002/sim.1783
Hilton TJ. Keys to clinical success with pulp capping: a review of the literature. Oper Dent. 2009;34:615-625. doi: 10.2341/09-132-0
Elchaghaby MA, Moheb DM, El Shahawy OI, et al. Clinical and radiographic evaluation of indirect pulp treatment of young permanent molars using photo-activated oral disinfection versus calcium hydroxide: a randomized controlled pilot trial. BDJ Open. 2020;6:4. doi: 10.1038/s41405-020-0030-z
Parirokh M, Torabinejad M. Mineral trioxide aggregate: a comprehensive literature review – part I: chemical, physical, and antibacterial properties. J Endod. 2010;36:16-27. doi: 10.1016/j.joen.2009.09.006
Lee SJ, Monsef M, Torabinejad M. Sealing ability of a mineral trioxide aggregate for repair of lateral root perforations. J Endod. 1993;19:541-544. doi:10.1016/S0099-2399(06)81282-3
Pushpalatha C, Dhareshwar V, Sowmya SV, et al. Modified mineral trioxide aggregate-a versatile dental material: an insight on applications and newer advancements. Front Bioeng Biotechnol. 2022;10:941826. doi:10.3389/fbioe.2022.941826
Alqahtani AS, Alsuhaibani NN, Sulimany AM, Bawazir OA. NeoPUTTY® versus NeoMTA 2® as a pulpotomy medicament for primary molars: a randomized clinical trial. Pediatr Dent. 2023;45(3):240-244.
Aeinehchi M, Eslami B, Ghanbariha M, Saffar AS. Mineral trioxide aggregate (MTA) and calcium hydroxide as pulp-capping agents in human teeth: a preliminary report. Int Endod J. 2003;36:225-231. doi: 10.1046/j.1365-2591.2003.00652.x
Nair M, Gurunathan D. Clinical and radiographic outcomes of calcium hydroxide vs other agents in indirect pulp capping of primary teeth: a systematic review. Int J Clin Pediatr Dent. 2019;12(5):437-444. doi: 10.5005/jp-journals-10005-1672
Gandolfi MG, Siboni F, Botero T, Bossù M, Riccitiello F, Prati C. Calcium silicate and calcium hydroxide materials for pulp capping: biointeractivity, porosity, solubility and bioactivity of current formulations. J Appl Biomater Funct Mater. 2015;13:41-60. doi: 10.5301/jabfm.5000201.
Jantarat J, Ritsayam S, Banomyong D, Chaimanakarn C. Early and 24-hour shear bond strength to dentine of three calcium silicate based pulp capping materials. Mah Dent J. 2018;38:177-183.
Malkondu Ö, Karapinar Kazandağ M, Kazazoğlu E. A review on biodentine, a contemporary dentine replacement and repair material. Biomed Res Int. 2014;2014:160951. doi: 10.1155/2014/160951
Saber AM, El Meligy OA, Alaki SM. Recent advances in indirect pulp treatment materials for primary teeth: a literature review. Int J Clin Pediatr Dent. 2021;14(6):795-801. doi: 10.5005/jp-journals-10005-2073
Kunert M, Lukomska-Szymanska M. Bio-inductive materials in direct and indirect pulp capping-a review article. Materials (Basel). 2020;13(5):1204. doi: 10.3390/ma13051204
Acharya S, Gurunathan D, Sahoo D, Singh B, Sahoo A, Acharya S. Comparative Evaluation of the Antimicrobial Activity of NeoPutty MTA and Modified NeoPutty MTA: An In Vitro Study. J Int Soc Prev Community Dent. 2023;13(6):493-499. doi: 10.4103/jispcd.JISPCD_68_23
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