Clostridium difficile – associated disease (CDAD) in patients hospitalized at the Medical Center in Łańcut – a retrospective study

Authors

  • Marta Musz-Kawecka „Centrum Medyczne w Łańcucie” Spółka z ograniczoną odpowiedzialnością
  • Marcin Hawro „Centrum Medyczne w Łańcucie” Spółka z ograniczoną odpowiedzialnością
  • Krzysztof Golec Uniwersytet Rzeszowski, Wydział Medyczny, Instytut Fizjoterapii

Keywords:

Clostridium difficile-associated disease, hospital- acquired infections, recurrence

Abstract

Introduction: Due to a substantial increase in infections caused by Clostridium difficile, in particular hospital-acquired infections, an interest in this issue, as well as prevention, diagnosis and therapy of Clostridium difficile – associated Disease (CDAD) is increasing worldwide (1). Health-careassociated Clostridium difficile infections are prevalent among infections caused by Clostridium difficile, which results both from external study (2) and the research carried out and included in this work. Healthcare associated infections depend on hospitalization and hospital environment (3) so it is important to identify the epidemiological situation caused by Clostridium difficile in Polish hospitals.

Aim: This work examines the incidence of Clostridium difficile – associated Disease, narrowing down the data to the ones obtained from the Medical Center in Łańcut in 2009–2011.

Results: The research carried out shows that the studied population and the environment reflect the findings of the main world centers. A general increase in the incidence among hospitalized patients, the convergence of risk factors, including those age-related and connected with antibiotic therapy, and the incidence of recurrence have been confirmed. Furthermore, a certain regularity was observed, indicating that Clostridium difficile is one of the major causes of diarrhea in hospitalized patients. The significance of the problem of Clostridium difficile infection is also indicated by a growing number of CDAD incidence in a non-hospital population.

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References

Martirosian G. Clostridium difficile: do czego zmierzamy? Postępy w medycynie zakażeń; X Jubileuszowe Sympozjum Naukowe. 1, 2006, strony 65-69.

Hryniewicz W. Martirosian G., Ozorowski T.,. Zakażenia C. difficile - diagnostyka, terapia, profilaktyka. Narodowy Program Ochrony Antybiotyków, Moduł I - Monitorowanie zakażeń szpitalnych oraz nwazyjnych zakażeń bakteryjnych dla celów epidemiologicznych, terapeutycznych i profilaktycznych na lata 2009-2013. 2011, 1.

Stuart H. Cohen Dale N. Gerding, Stuart Johnson. SHEA-IDSA guideline. Clinical Practice Guidelines for Clostridium difficile infection in Adults: 2010. Infection control and hospital epidemiology. 2010, Tom 31, 5.

Barbut F. Decré D., Lalande V. and other authors. Clinical features of Clostridium difficile-associated diarrhoea due to binary toxin (actin-specific ADP-ribosyltransferase)-producing strains. 2005, Tom 54, strony 181-185.

Lyerly T.D. Wilkins and D.M. Clostridium difficile Testing: after 20 Years, Still Challenging. Journal of Clinical Microbiology. 41, 2003, strony 531-34.

Bauer M. Notermans D., van Benthem B. i wsp. Clostridium difficile infection in Europe: a hospital-based survey. Lancet. 2011, Tom 377, strony 63-73.

Kyne L. Warny M., Qamar A. i wsp. Association between antibody response to toxin A and protection against recurrent Clostridium difficile diarrhea. Lancet. 2001, 357, strony 189-193.

Published

2013-09-30

How to Cite

Musz-Kawecka, M., Hawro, M., & Golec, K. (2013). Clostridium difficile – associated disease (CDAD) in patients hospitalized at the Medical Center in Łańcut – a retrospective study. European Journal of Clinical and Experimental Medicine, 11(3), 342–355. Retrieved from https://journals.ur.edu.pl/ejcem/article/view/12633