The application of biosensors in tumor diagnostics

Authors

  • Paulina Cynk Koło Naukowe “Bio-Tech” Zamiejscowy Wydział Biotechnologii Uniwersytetu Rzeszowskiego
  • Ewelina Gaweł Koło Naukowe “Bio-Tech” Zamiejscowy Wydział Biotechnologii Uniwersytetu Rzeszowskiego

Keywords:

biosensing techniques, nanotechnology, neoplasms, diagnostics

Abstract

According to WHO report, cancer is one of the leading reasons of human death worldwide, accounting for around 13% of all deaths (7,6 million all deaths)[1]. One of the causes is late diagnosis of cancer. Recently, biosensors seem to be a good solution to help solve that problem. Biosensors are devices consisting of two components: a biological one, which reacts with analyzed substance, and an analitical component, which generates and transduces the signal. The paper is discussing about the most popular biosensor types and the way they work. It also shows examples of use, with impact on perspectives concerning cancer diagnosis.

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References

http://www.who.int/mediacentre/factsheets/fs297/en/index.html

Mohanty S, Kougianos E. Biosensors: a tutorial review. IEEE Potentials 2006;25:35-40.

Rogers K. Cancer Research - Nanoparticles, nanobiosensors and their use in cancer research. Journal of Nanotechnology Online 2006;3:1-14.

Newman JD, Tigwell LJ, Warner PJ, Turner APF. Biosensors: boldly going into the new millennium. Sensor Review 2001;21:268 – 271.

Higson SPJ, Reddy SM, Vadgama PM. Enzyme and other biosensors: evolution of a technology. Eng Sci Educ J 1994;3:41–48.

Kissinger PT. Biosensors- a perspective. Biosens Bioelectron 2005;20:2512–2516.

Chambers JP, Arulanandam BP, Matta LL, Weis A, Valdes JJ. Biosensor Recognition Elements. Curr Issues Mol Biol 2008;10:1–12.

Van Staden JF, Aboul-Enein HJ, Stefan RI. Biosensor Technology. W: Cazes J. Analytical Instrumentation Handbook- Second Edition 2004:681-686.

Bohunicky B, Mousa AS. Biosensors: the new wave in cancer diagnosis. Nanotechnology, Science and Applications 2011:4 1–10.

Thévenot DR, Toth K, Durst RA, Wilson GS. Electrochemical Biosensors: Recommended Definitions and Classification (Technical Report). Biosens Bioelectron 2001;16:121–131.

Shana A, Rogers KR. Biosensors. Meas Sci Technol 1994;5:461-472.

Rasooly A, Jacobson J. Development of biosensors for cancer clinical testing. Biosens Bioelectron 2006;21:1851–1858.

D'Orazio P. Biosensors in clinical chemistry. Clin Chim Acta 2003;334:41-69.

Rodriguez-Mozaz S, Marco MP, Lopez de Alda MJ, Barcelo D. Biosensors for environmental monitoring of endocrine disruptors: a review article. Anal Bioanal Chem. 2004;378:588-598.

Altschuh D. Immunochemistry and biosensors. http://esonn.fr/esonn2009/lectures09/Altschuh09.pdf (2008)

Reder-Christ K, Bendas G. Biosensor Applications in the Field of Antibiotic Research—A Review of Recent Developments. Sensors 2011;11:9450–9466.

The´venot DR, Toth K, Durst RA, Wilson GS. Electrochemical biosensors: recommended definitions and classification. Biosens Bioelectron 2001;16:121–131.

Khalil AS, Collins JJ. Synthetic biology: applications come of age. Nat Genet 2010;11:367-379.

Garipcan B, Çalayan MO, Demirel G. New Generation Biosensors Based on Ellipsometry. W: Serra P.A. New Perspectives in Biosensors Technology and Applications 2011:197-214.

Doria G, Conde J, Veigas B, Giestas L, Almeida C, Assunço M i wsp. Noble Metal Nanoparticles for Biosensing Applications. Sensors 2012;12:1657–1687.

Rodriguez-Mozaz S, Lopez de Alda MJ, Barceló D. Biosensors as useful tools for environmental analysis and monitoring. Anal Bioanal Chem 2006;86:1025–1041.

Turner AP. Biosensors – sense and sensitivity. Science 2000;290:1315–1317.

Sadana A. Biosensors: Kinetics of binding and dissociation using fractals. Elsevier B.V. 2003:57-158

Hong P, Li W, Li J. Applications of Aptasensors in Clinical Diagnostics. Sensors 2012;12:1181–1193.

Tuzel A. Wszechstronne detektory - aptamery nukleinowe. http://bioinfo.mol.uj.edu.pl/articles/Tuzel06 (2006)

Soper SA, Brown K, Ellington A, Frazier B, Garcia-Manero G, Gau V. Point-of-care biosensor systems for cancer diagnostics/prognostics. Biosens Bioelectron 2006;15:1932-1942.

Myung S, Solanki A, Kim C, Park J, Kim KS, Lee KB. Graphene-Encapsulated Nanoparticle-Based Biosensor for the Selective Detection of Cancer Biomarkers. Adv Mater 2011;17:2221–2225.

Wang J. Electrochemical biosensors: Towards point-of-care cancer diagnostics. Biosens Bioelectron 2006;21:1887–1892.

Kim MJ, Jeong S. In Vitro Selection of RNA Aptamer and Specific Targeting of ErbB2 in Breast Cancer Cells. Nucleic Acid Ther 2011;21:173–178.

Liu Y, Tuleouva N, Ramanculov E, Revzin A. Aptamer-based: Electrochemical Biosensor for Interferon Gamma Detection. Anal Chem 2010;1:8131–8136.

Zhou WI, Ma Y, Yang H, Ding Y, Luo X. A label-free biosensor based on silver nanoparticles array for clinical detection of serum p53 in head and neck squamous cell carcinoma. Int J Nanomedicine 2011;6:381–386.

Chow V, Yuen AP, Lam KY, Ho WK, Wei WI. Prognostic significance of serum p53 protein and p53 antibody in patients with surgical treatment for head and neck squamous cell carcinoma. Head Neck 2001;4:286-291.

Alloush HM, Anderson E, Martin AD, Ruddock MW, Angell JE, Phil J i wsp. A Bioluminescent Microbial Biosensor for In Vitro Pretreatment Assessment of Cytarabine Efficacy in Leukemia. Clinical Chemistry 2011;56:1862-1870.

Strosnider H. Whole-Cell Bacterial Biosensors and the Detection of Bioavailable Arsenic. for U.S. Environmental Protection Agency, 2003

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Published

2012-09-30

How to Cite

Cynk, P., & Gaweł, E. (2012). The application of biosensors in tumor diagnostics. European Journal of Clinical and Experimental Medicine, 10(3), 373–378. Retrieved from https://journals.ur.edu.pl/ejcem/article/view/12738

Issue

Vol. 10 No. 3 (2012): Medical Journal of the Rzeszow University and the National Medicines Institute, Warsaw

Section

REVIEW PAPERS

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Copyright (c) 2012 Medical Journal of the Rzeszow University and the National Medicines Institute, Warsaw

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