Different clinical picture of coeliac disease in children
Keywords:
coeliac disease, gluten, gluten-free dietAbstract
Introduction: It has been observed that the coeliac disease (CD) incidence rate has increased in recent years. CD’s first symptoms are uncharacteristic and may hinder an accurate diagnosis. Making an early diagnosis and going on a glutenfree diet improve patients’ quality of life and prevent the development of potential complications.
Objective: The aim of this study was to analyse clinical manifestations of coeliac disease during development and to identify specific symptoms of the disease for individual age groups.
Materials and methods: The study was based on the medical documentation of inpatients of the Clinic of Paediatrics, Medical University of Lublin, who stayed in the clinic between 2005 and 2010 and who were first diagnosed with coeliac disease. The patients were divided into two groups. Children under six were in group 1 and children over six were in group 2. The study accounted for the incidence rate of clinical symptoms considering the patients’ age and sex, accompanying diseases and a family history aimed at coeliac disease. Statistica 5.0. software was used for statistical analysis.
Results: 13 children aged two to 15 were diagnosed with coeliac disease at the Clinic of Paediatrics at the time when the study was conducted. The most common symptoms among patients from group 1 were weight deficiency (83,33 percent), height deficiency and aerenterectasia (50,00 percent each). The most common symptoms among patients from group 2 were microcytic anaemia (57,14 percent), weight deficiency and height deficiency (42,86 percent each), abdominal pain (28,57 percent). Differences in the clinical picture of the disease considering the patients’ age and sex were not statistically significant (p=0, 55; p=0, 77 respectively).
Conclusions: Coeliac disease manifests itself with many symptoms, appears in an uncharacteristic or asymptomatic way. It has been proved that there are differences in the clinical picture of the disease among individual age groups.
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