Replication of bacterial plasmids and antiplasmid therapy
Abstract
Multiple resistance genes are coded on plasmids transferred by pathogenic microorganisms. Due to increasing drug resistance among microorganisms studying on plasmids provides data useful in searching for new methods of eradication of multidrug resistant bacteria. Replication is a fundamental process that leads to inheritance plasmids by host cells. Replication control system maintains the number of plasmid copies on a certain level in the host cells. The elements of control system become targets for antiplasmid therapies, which try to eradicate plasmids from host cells together with resistance genes.
Supporting Agencies
plasmid replication control of replication incompatybility antiplasmid therapyDownloads
References
Hawkey P. M.: The growing burden of antimicrobial resistance. Journal of Antimicrobial Chemotherapy 2008; 62: Suppl. 1: i1 – i9
DeNap J. C. B., Hergenrother P. J.: Bacterial death comes full circle: targeting plasmid replication in drug-resistant bacteria. Organic and Biomolecular Chemistry 2005; 3: 959 – 966
Holmes M. L., Pfeifer F., Dyall – Smith M. L.: Analysis of the halobacterial plasmid pHK2 minimal replicon. Gene 1995; 153: 117 – 121
Baj J., Markiewicz Z. [red.]: Biologia molekularna bakterii. Wydawnictwo Naukowe PWN Warszawa 2006
Novick R. P.: Plasmid incompatybility. Microbiological Reviews 1987, 51: 381 – 396
Włodarczyk M.: Co to jest plazmid? Kosmos 2002; 51: 231 – 240
Bergstrom C. T., Lipsitch M., Levin B. R.: Natural selection, infectious transfer and the existence conditions for bacterial plasmids. Genetics 2000; 155: 1505–1519
Couturier M., Bex F., Bergquist P. L., Maas W. K.: Identification and classification of bacterial plasmids. Microbiological Reviews 1988; 52: 375 – 395
Del Solar G., Giraldo R., Ruiz-Echevarria M. J., Espinosa M., Diaz – Orejas R.: Replication and control of circular bacterial plasmids. Microbiology and Molecular Biology Reviews 1998; 62: 434 – 464
Meinhardt F., Schaffrath R., Larsen M.: Microbial linear plasmids. Applied Microbiological Biotechnology 1997; 47: 329 – 336
Wróbel B.: Replikacja plazmidów. Kosmos (2002); 51: 255 – 272
Soler N., Marguet E., Cortez D., Desnoues N., Keller J., Van Tilbeurgh H.: Two novel families of plasmids from hyperthermophilic archaea encoding new families of replication proteins. Nucleic Acids Research 2010; 1–17
Khan S. A.: Plasmid rolling – circle replication: recent developments. Molecular Microbiology 2000; 37: 477 – 484
Chattoraj D. K.: Control of plasmid DNA replication by iterons: no longer paradoxical. Molecular Microbiology 2000; 37: 467 – 476
Del Solar G., Espinosa M.: Plasmid copy number control: an ever – growing story. Molecular Microbiology 2000; 37: 492 – 500
Das N., Valjavec-Gratian M., Basuray A. N., Fekete R. A., Papp P. P., Paulsson J.: Multiple homeostatic mechanisms in the control of P1 plasmid replication. The Proceedings of The National Academy of Sciences 2005; 102: 2856–2861
Caratolli A.: Resistance plasmid families in Enterobacteriaceae. Antimicrobial Agents and Chemotherapy 2009; 53: 2227 – 2238
Caratolli A., Bertini A., Villa L., Falbo V., Hopkins K. L., Threlfall E. J.: Identification of plasmids by PCR – based replicon typing. Journal of Microbiological Methods 2005; 63: 219 – 228
Götz A., Pukall R., Smit E., Tietze E., Prager R., Tschäpe H.: Detection and characterization of broad-host-range plasmids in environmental bacteria by PCR. Applied and Environmental Microbiology 1996; 62: 2621–2628
Johnson T. J., Wannemuehler Y. M., Johnson J. S., Logue C. M., White D. G., Doetkott C.: Plasmid replicon typing of commensal and pathogenic Escherichia coli isolates. Applied and Environmental Microbiology 2007; 73: 1976 – 1983
Lindsey R. L., Fedorka-Cray P. J., Frye J. G., Meinersmann R. J.: Inc A/C plasmids are prevalent in multidrug-resistant Salmonella enterica isolates. Applied and Environmental Microbiology 2009; 75: 1908 – 1915
Marcadé G., Deschamps C., Boyd A., Gautier V., Picard B., Branger C.: Replicon typing of plasmids in Escherichia coli producing extended-spectrum b-lactamases. Journal of Antimicrobial Chemotherapy 2009; 63: 67–71
Sherley M., Gordon D. M., Collignon P. J.: Species differences in plasmid carriage in the Enterobacteriaceae. Plasmid 2003; 49: 79–85
Zhong Z., Helinski D., Toukdarian A.: Plasmid host-range: restrictions to F replication in Pseudomonas. Plasmid 2005; 54: 48–56
Francia V. M., Varsaki A., Garcillán-Barcia M. P., Latorre A., Drainas C., De la Cruz F.: A classification scheme for mobilization regions of bacterial plasmids. FEMS Microbiology Reviews 2004; 28: 79–100
Okinaka R. T., Cloud K., Hampton O., Hoffmaster A. R., Hill K. K., Keim P.: Sequence and organization of pXO1, the large Bacillus anthracis plasmid harboring the anthrax toxin genes. Journal of Bacteriology 1999, 181: 6509 – 6515
Pannucci J., Okinaka R. T., Sabin R., Kuske C. R.: Bacillus anthracis pXO1 plasmid sequence conservation among closely related bacterial species. Journal of Bacteriology 2002; 184: 134 – 141
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