Features of diagnostics, clinical course and treatment of helicobacter pylori infection in children

Authors

  • Serhiy Nyankovskyy Danylo Halytskiy Lviv National Medical University, Lviv, Ukraine
  • Olena Ivakhnenko Danylo Halytskiy Lviv National Medical University, Lviv, Ukraine

Keywords:

gastritis, gastroduodenitis, stomach ulcer, Helicobacter pylori, diagnostics, treatment, eradication

Abstract

The article is devoted to study of endoscopic, morphologic and clinical features of the course of chronic diseases of the upper parts of digestive system associated with Helicobacter pylori infection in children. The age prevalence of gastrointestinal diseases among schoolchildren, features of their accommodation, nutrition, and education were studied using screening questionnaire. Comparative efficacy of several invasive and non-invasive Helicobacter pylori diagnostic techniques in children was tested. The diagnostic value of qualitative Helicobacter pylori stool antigen test employing and comparative efficacy of different methods of eradication therapy (triple- and quadro-) based on using bismuth containing drugs and the proton pump inhibitors were studied. The tolerance and frequency of side effects associated with the use of eradication therapy were investigated.

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References

Aruin L.I., Capuller L.L., Isakov V.A.: Morphological diagnostics of stomach and intestines diseases, Moscow, 1998.

Balli F., Pancaldi M.E., Viola L.: Helicobacter pylori. Part II. Epidemiology, diagnosis, and treatment, Pediatr. Med. Chir. 2000; 21 (4): 165.

Bielanski W.: Epidemiological study on Helicobacter pylori infection and extragastroduodenal disorders in Polish population, J. Physiol. Pharmacol. 1999; 50 (5): 817.

Blaser M.J., Clinical review. Science, medicine, and the future. Helicobacter pylori and gastric diseases, BMJ. 1998; 316: 1507.

Corsunskiy А.А., Scherbakov P.L., Isakov V.А.: Helicobacteriosis and gastro-duodenal diseases in children, Moscow, 2002.

Drumm В., Koletzko S.: Oderda G. European Task Force on Helicobacter pylori infection in children, J. Pediatr. Gastroenterol. Nutr. 2000; 31: 207.

Ernst P.B., Gold B.D.: The Disease Spectrum of Helicobacter pylori: the immunopathogenesis of gastroduodenal ulcer and gastric cancer, Ann. Rev. Microbiol. 2000; 54: 615.

Graham D.Y.: Antibiotic resistance in Н. pylori: implications for therapy, Gastroenterology 1998; 115: 1272.

Hp Infection in Children: A Consensus Statement, J. Pediatr. Gastroenterol. Nutr., 2000; 30: 207.

Lee A., Megraud F.: Helicobacter pylori. Techniques for clinical diagnosis and basic research, Saunders – London. Sec. Print.- 1996.

Malfertheiner P., Megraud F., O’Morain C. at al.: Current European concepts in the management of Helicobacter pylori infection. The Maastricht 2–2000 Consensus Report. Aliment. Pharmacol.Ther. 2002; 16 (2): 167.

Marshall B.J.: H.pylori. Amer. J. Gastroenterology 1994; 89 (8): 116.

Megraud F.: Rationale for the choice of antibiotics for the eradication Helicobacter pylori, Eur J Gastroenterol 1995; 1: 49.

NASPGHAN Medical Position Paper: „Hp Infection in Children: Recommendations for Diagnosis and Treatment”. J. Pediatr Gastroenterol. Nutr. 2000; 31: 490.

Nyankovskyy S., Vdovichenko V., Ivakhnenko O. Vdovichenko A.: Character rodzinny zakazenia Helicobacter Pylori: podejscie do leczenia i profilaktyki, Pediatria Wspolczesna. Gastroenterologia, Hepatologia i Zywienie Dziecka 2000; 3 (2): 181.

Nyankovskyy S., Ivakhnenko O.: Family approaches to estimate risk factors, diagnostics and treatment of Helicobacter Pylori infection. Approved Abstracts for Children’s Environmental II: A Global Forum for Action. 2002 Washington 14.

Nyankovskyy S.L., Denysova M.F., Ivakhnenko O.S.: A comparative efficiency of helicobacter infection diagnosing methods in children with gastro-duodenal zone diseases and eradication therapy patterns. J.of Current Pediatrics. 2004; 4(5): 57.

Nyankovskyy S.L., Ivakhnenko O.S.: Comparative efficacy of main protocols of antihelicobacter therapy in children, Drugs of Ukraine 2004; 11:75.

Nyankovskyy S.L., Denysova M.F., Ivakhnenko O.S., Ivantsiv V.A.: The peculiarities of diagnostics, clinical course and treatment of helicobacteriosis in children, Modern Gastroenterology 2005; 1 (21): P. 65.

Perederiy V.G, Tkach S.M., Grygorenko A.A. Tsvetkov A.V.: Main reasons of global epidemiological change of Helicobacter Pylori infection and dependant diseases, Modern Gastroenterology 2001; 2 (4): 3.

Roma–Giannikou E., Karameris A., Balatsos B. at al.: Intrafamilial spread of Helicobacter pylori: A genetic analysis. Helicobacter 2003; 8: 15.

Rozynek E., Dzierzanowska–Fangrat K., Celinska–Cedro D. et al.: Primary resistance of Helicobacter pylori to antimicrobial agents in Polish children. Acta. Microbiol. Pol. 2002; 51 (3): 255.

Scherbakov P.L., Vartapetova E.E., Filin V.A.,Salmova V.S.: Algorithm of modern diagnostics and treatment for Helicobacter Pylori infection in children with chronic diseases of upper parts of the digestive system, Paediatrics 2003; 6: 86.

Vaira D., Malfertheiner P., Megraud F., at al. HpSA European Study Group. Diagnosis of Helicobacter pylori infection with a new non-invasive antigen-based assay. Lancet 1999; 354: 30.

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Published

2007-03-30

How to Cite

Nyankovskyy, S., & Ivakhnenko, O. (2007). Features of diagnostics, clinical course and treatment of helicobacter pylori infection in children. European Journal of Clinical and Experimental Medicine, 5(1), 41–49. Retrieved from https://journals.ur.edu.pl/ejcem/article/view/13367