Generation of retractive spine circuits in the process of vitamin B12 deficiency

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DOI:

https://doi.org/10.15584/ejcem.2020.2.9

Keywords:

ataxia, B12 avitaminosis, retinal spinal cord degeneratio

Abstract

Introduction. Subacute degeneration of the posterior and lateral spinal cord is a rare neurological complication of B12 avitaminosis.

Aim. In this paper, we present the case of a 65-year-old man who, in the course of long-term vitamin B12 deficiency associated with atrophic gastritis, developed a severe set of neurological symptoms that are part of the retinal spinal cord degeneration with characteristic features in MR imaging of the cervical spine in the form of an inverted “V mark” ‘in axial images and typical localization in the spinal cord.

Description of the case. After careful analysis of the syndrome and making an early diagnosis, parenteral vitamin B12 supplementation began, resulting in improved neurological status, laboratory parameters as well as regression of changes in magnetic resonance imaging.

Conclusion Significant symptoms of this syndrome are paresthesia in the distal parts of the limbs, ataxia, spastic paresis.

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References

Rodriguez-Castro KI, Franceschi M, Noto A, et al. Clinical manifestations of chronic atrophic gastritics. Acta Biomed. 2018;89(8-S):88-92.

Lanier JB, Park JJ, Callahan RC. Anemia in Older Adults. Am Fam Physician. 2018;98(7):437-442.

Zhang HN, Wang L, Sun L, Yang Y. Three-point sign in subacute combined degeneration of the spinal cord: A case report. Medicine (Baltimore). 2018;97(31):e11620.

Pearce MC, Choy G, ChenMark RC. Clinics in diagnostic imaging. Subacute combined degeneration of spinal cord Singapore. Med J. 2010;59(9):460-464.

Langan RC, Zawistoski KJ. Update on vitamin B12 deficiency. Am Fam Physician. 2011;83(12):1425-1430.

Anderson WD 3rd, Strayer SM, Mull SR. Common questions about the management of gastroesophageal reflux disease. Am Fam Physician. 2015;91(10):692-697.

Langan RC, Goodbred AJ. Vitamin B12 deficiency. Recognition and Management. AM Fam Physician. 2000;67(5):979-989.

Loveland P, Wong A, Vivekanandam V, Lim WK. Subacute combined degeneration of the spinal cord masking motor neuron disease: a case report. J Med Case Rep. 2019;18;13(1):336.

Spoelhof GD. Reliability of serum B12 levels in the diagnosis of B12 deficiency. Am Fam Physician. 1996;54(2):465-468.

Ravina B, Loevner LA, BankW. MR. Findings in subacute combined degeneration of the spinal cord, a case of reversible cervical myelopathy. Am J Roentgenol. 2000;174:863-865.

Gürsoy AE, Kolukısa M, Babacan-Yıldız G, Celebi A. Subacute Combined Degeneration of the Spinal Cord due to different etiologies and improvement of MRI Findings. Case Rep Neurol Med. 2013;2013:159649.

Jung JB, Kim Y, Oh K, Kim SA, Doh JH, Oh HJ, Seok JM. Subacute combined degeneration associated with vitamin E deficiency due to small bowel obstruction. Medicine. 2019;98(36) e17052.

Irwin JJ, Kirchner JT. Anemia in children. Am Fam Physician. 2001;64(8):1379-1386.

Clementz GL, Schade SG. The spectrum of vitamin B12 deficiency. Am Fam Physician. 1990;41(1):150-162

Canas N, Calado S, Ribeiro C, Vale J. Reversible cervical hydromyelia in subacute combined degeneration. Neurology. 2005;65(3):E7.

Ravina B, Loevner LA, Bank W. MR findings in subacute combined degeneration of the spinal cord: a case of reversible cervical myelopathy. AJR Am J Roentgenol. 2000;174(3):863-865.

Locatelli ER, Laureno R, Ballard P, Mark AS. MRI in vitamin B12 deficiency myelopathy. Can J Neurol Sci. 1999;26(1):60-63.

Nouri A, Patel K, Montejo J, et al. The Role of Vitamin B12 in the Management and Optimization of Treatment in Patients With Degenerative Cervical Myelopathy. Global Spine J. 2019;9(3):331-337.

Puntambekar P, Basha MM, Zak IT, Madhavan R. Rare sensory and autonomic disturbances associated with vitamin B12 deficiency. J Neurol Sci. 2009;287(1-2):285-287.

Senol MG, Sonmez G, Ozdag F, Saracoglu M. Reversible myelopathy with vitamin B12 deficiency. Singapore Med J. 2008;49(11):e330-e332.

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Published

2020-06-30

How to Cite

Mucha, P., Leksa, D., Aebisher, D., Galiniak, S., Bartosz, S., Leksa, N., & Bartusik-Aebisher, D. (2020). Generation of retractive spine circuits in the process of vitamin B12 deficiency. European Journal of Clinical and Experimental Medicine, 18(2), 131–134. https://doi.org/10.15584/ejcem.2020.2.9

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