The larynx cancer in vitro study by MRI relaxtion time of water
DOI:
https://doi.org/10.15584/ejcem.2020.3.5Keywords:
larynx tissue, magnetic resonance imaging, T2 mapping, T2 relaxation timeAbstract
Introduction. Squamous cell carcinoma (SCC) of the larynx accounts for a significant percentage of all head and neck cancers.
Aim. In this paper we determine the differences in magnetic resonance relaxation time (MRI) of water in cancerous and healthy larynx tissues.
Material and methods. This study is aimed on T2 MRI modalities for monitoring morphology of larynx tissue.
Results. Our results showed that T2 MRI relaxation time measured in larynx tissue can be used to assess early cancer condition of larynx tissues. The changes of T2 MRI correspond to tumor growth within normal tissue.
Conclusion. The study showed potential of MRI for the non-invasive monitoring of larynx condition.
Downloads
References
Filippi M, Charil A, Rovaris M, et al. Insights from magnetic resonance imaging. Handb. Clin Neurol. 2014;122:115 -149.
Young RJ, Knopp EA. J. Young RJ, et al. Brain MRI: tumor evaluation. Magn Reson Imaging. 2006;24:709-724.
Bottomley PA, Hardy CJ, Argersinger RE. A review of 1H NMR relaxation in pathology: are T1 and T2 diagnostic? Med Phys. 1987;1:1-37.
Bottomley PA, Foster TH, Argersinger RE, A review of normal tissue ... species, excision, and age. Med Phys. 1984;11:425.
Allisy-Roberts P. Farr's Physics for Medical Imaging. Eng. 2. ed. Edinburgh, New York: Saunders, 2007.
Welsch GH, Hennig FF, Krinner S. T2 and T2* Mapping. Curr Radiol Rep. 2014;2:60.
Cavaliere C, Romeo V, Aiello M, et al. Multiparametric evaluation by simultaneous PET-MRI examination in patients with histologically proven laryngeal cancer. Eur J Radiol. 2017;88:47-54.
Allegra E, Ferrise P, Trapasso S, et al. Early Glottic Cancer: Role of MRI in the Preoperative Staging. Biomed Res Int. 2014;890385.
Blitz AM, Aygun N. Otolaryngol. Radiologic evaluation of larynx cancer. Clin North Am. 2008;41:697.
Agnello F, Cupido F, Sparacia G, et al. Computerised tomography and magnetic resonance imaging of laryngeal squamous cell carcinoma: a practical approach Neuroradiol J. 2017;30: 197-205.
Jager EA, Ligtenberg H, Caldas-Magalhaes J, et al. Validated guidelines for tumor delineation on magnetic resonance imaging for laryngeal and hypopharyngeal cancer. Acta Oncol. 2016;55:1305 -1311.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2020 European Journal of Clinical and Experimental Medicine

This work is licensed under a Creative Commons Attribution 4.0 International License.
Our open access policy is in accordance with the Budapest Open Access Initiative (BOAI) definition: this means that articles have free availability on the public Internet, permitting any users to read, download, copy, distribute, print, search, or link to the full texts of these articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose, without financial, legal, or technical barriers other than those inseparable from having access to the Internet itself.
All articles are published with free open access under the CC-BY Creative Commons attribution license (the current version is CC-BY, version 4.0). If you submit your paper for publication by the Eur J Clin Exp Med, you agree to have the CC-BY license applied to your work. Under this Open Access license, you, as the author, agree that anyone may download and read the paper for free. In addition, the article may be reused and quoted provided that the original published version is cited. This facilitates freedom in re-use and also ensures that Eur J Clin Exp Med content can be mined without barriers for the research needs.




