Hyperaminotransferasemia –in daily practice of a paediatrician and general practitione
Keywords:
hyperaminotransferasemia, children, differential diagnosis, liver diseases, muscular diseasesAbstract
Hyperaminotransferasemia — elevated liver enzymes, is one of the most frequently observed abnormali-ties in the lab studies. It is present in many various diseases such as: liver or neuro-muscular disorders, in-born errors of metabolism, drug side effects and many others. Therefore differential diagnosis remains a difficult problem in the daily practice of many specialists, but first and foremost of a general practitioner and paediatrician. While diagnosing a patient with elevated liver enzymes a cilnicist must firstly think of the most frequent diseases, secondly of more rare disorders. It is believed that following aspects should be con-sidered in the diagnosis: clinical symptoms, duration, complementary lab tests, imaging. Only appropriate differential diagnosis should lead to a truthful diagnosis and adequate treatment.
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