Premature thelarche – pathogenesis and management

Authors

  • Aleksandra Januszek-Trzciąkowska Z Katedry i Kliniki Pediatrii, Endokrynologii i Diabetologii Dziecięcej Śląskiej Akademii Medycznej w Katowicach
  • Ewa Małecka-Tendera Z Katedry i Kliniki Pediatrii, Endokrynologii i Diabetologii Dziecięcej Śląskiej Akademii Medycznej w Katowicach
  • Maria Kalina Z Katedry i Kliniki Pediatrii, Endokrynologii i Diabetologii Dziecięcej Śląskiej Akademii Medycznej w Katowicach
  • Barbara Kalina-Faska Z Katedry i Kliniki Pediatrii, Endokrynologii i Diabetologii Dziecięcej Śląskiej Akademii Medycznej w Katowicach

Keywords:

premature thelarche, children

Abstract

Precocious breast development in girls (thelarche praecox) is an isolated variant of precocious puberty, regressing spontaneously in vast majority of patients. Pathogenesis of this phenomenon has not been identified. Most authors explain it by incomplete activation of the hypothalamic-pituitary-gonadal axis or by hypersensitivity of the glandular tissue to low, physiological fluctuations of estrogens concentrations. From the clinical point of view the most essential is to differentiate this form from true central precocious puberty, as well as to carefully follow up intermediate variants which may exhibit slow progression.

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Published

2006-12-30

How to Cite

Januszek-Trzciąkowska, A., Małecka-Tendera, E., Kalina, M., & Kalina-Faska, B. (2006). Premature thelarche – pathogenesis and management. European Journal of Clinical and Experimental Medicine, 4(4), 302–305. Retrieved from https://journals.ur.edu.pl/ejcem/article/view/13387

Issue

Vol. 4 No. 4 (2006): Medical Journal of the Rzeszow University

Section

REVIEW PAPERS

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Copyright (c) 2006 Medical Journal of the Rzeszow University

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