A patient with overlap syndrome: systemic lupus erythematosus, dermatomyositis, and Sjögren’s syndrome – a rare overlapping diseases case report

Authors

  • Aldona Sokołowska Student Scientific Association at the Department of Human Immunology, Institute of Medical Sciences, Medical College of Rzeszow University, University of Rzeszow, Rzeszow, Poland https://orcid.org/0009-0006-8723-2593
  • Mateusz Iwański Student Scientific Association at the Department of Human Immunology, Institute of Medical Sciences, Medical College of Rzeszow University, University of Rzeszow, Rzeszow, Poland
  • Piotr Dąbrowski Department of Rheumatology, Institute of Medical Sciences, Medical College of Rzeszow University, University of Rzeszow, Rzeszow, Poland https://orcid.org/0000-0001-5082-5391

DOI:

https://doi.org/10.15584/ejcem.2023.3.8

Keywords:

autoimmune diseases, overlap syndrome, self-reactive

Abstract

Introduction and aim. Autoimmune rheumatic diseases are a group of disorders with similar clinical, laboratory and immunological manifestations. Connective tissue diseases include systemic scleroderma, dermatomyositis or polymyositis, Sjögren’s syndrome, rheumatoid arthritis, and systemic lupus erythematosus. If the patient meets the diagnostic criteria for at least two of these diseases and has specific serologic markers, a diagnosis of overlap syndrome is possible.

Description of the case. This case describes a 27-year-old man who had a history of paroxysmal fever, night sweats, erythema-like skin lesions on the forearms and lower legs, a feeling of progressive muscle weakness especially in the proximal muscles, and dry mouth. The patient was diagnosed with an overlap syndrome: systemic lupus erythematosus, dermatomyositis, and Sjögren’s syndrome.

Conclusion. Overlap syndrome is difficult to treat due to its multisystem nature, requiring a symptomatic therapeutic approach and careful control of medication doses to reduce side effects while controlling disease activity.

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Published

2023-09-30

How to Cite

Sokołowska, A., Iwański, M., & Dąbrowski, P. (2023). A patient with overlap syndrome: systemic lupus erythematosus, dermatomyositis, and Sjögren’s syndrome – a rare overlapping diseases case report. European Journal of Clinical and Experimental Medicine, 21(3), 659–662. https://doi.org/10.15584/ejcem.2023.3.8

Issue

Vol. 21 No. 3 (2023)

Section

CASUISTIC PAPERS

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