Orbitofrontal cortex dysfunction and risk for antisocial behavior: An analytical review
Keywords:
orbitofrontal cortex, dysfunction, antisocial behavior, aggressionAbstract
Objective: This article is aimed to establish the relation between orbitofrontal cortex (OFC) dysfunction and antisocial behavior, based on a review of relevant literature.
Method: Materials presenting the role of OFC dysfunction in human behavioral disorders, including antisocial behavior, were collected through systematic survey of various sources, including MEDLINE, Google Scholar, academic libraries.
Results: Many studies showed prevalence of violent and antisocial behaviors in persons with frontal lobes damage, especially involving the OFC structures. The results support the assumption about association between focal orbitofrontal damage and increased risk of violent and aggressive behavior.
Conclusion: Neuropsychological and neuroimaging data from various filds within neuroscience provide evidence about importance of the OFC dysfunction as a predictor of violent and antisocial behavior.
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