Combined treatment of cervical pregnancy with methotrexate and prostaglandins. A case report

Authors

  • Grzegorz Raba Instytut Położnictwa i Ratownictwa Medycznego. Wydział Medyczny Uniwersytetu Rzeszowskiego; Wojewódzki Szpital w Przemyślu https://orcid.org/0000-0002-9196-8548
  • Kamil Szczupak Wojewódzki Szpital w Przemyślu
  • Piotr Baran Wojewódzki Szpital w Przemyślu

Keywords:

cervical pregnancy, methotrexate, prostaglandin, fertility

Abstract

Cervical pregnancy is the rarest form of ectopic pregnancy. Resulting from the interaction of the trophoblast-released proteolytic enzymes on the wall of large blood vessels cervical pregnancy may lead to massive, life-threatening haemorrhages. Methods of treatment preserving fertility encompass systemic or local administration of cytotoxic drugs. According to the literature, treatment with systemic application of cytotoxic drugs is ineffective when level of serum hCG is higher than 10000IU/ml. This report presents a case of effective conservative treatment preserving fertility in a woman with cervical pregnancy who had level of serum hCG 74000IU/ml. Clinical effectiveness was achieved by intravenous methotrexate and prostaglandin injections.

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References

Singh S. Diagnosis and management of cervical ectopic pregnancy. J Hum Reprod Sci 2013; 6, 273-6.

Surampudi K. A case of cervical ectopic pregnancy: successful therapy with methotrexate. J Obstet Gynaecol India 2012;62, 1-3.

Postawski K, Romanek K, Wróbel A, et al. Conservative treatment of cervical pregnancy in women:a review of the literature with case report. Ginekol Pol. 2009; 80, 704-707

Chrestiana D, Cheng AB, Panebianco N, et al. Pitfalls in cervical ectopic pregnancy diagnosis by emergency physicians using bedside ultrasonography. Am J Emerg Med 2013; 32,1-3.

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Published

2014-09-30

How to Cite

Raba, G., Szczupak, K., & Baran, P. (2014). Combined treatment of cervical pregnancy with methotrexate and prostaglandins. A case report. European Journal of Clinical and Experimental Medicine, 12(3), 309–312. Retrieved from https://journals.ur.edu.pl/ejcem/article/view/12565

Issue

Vol. 12 No. 3 (2014): Medical Journal of the Rzeszow University and the National Medicines Institute, Warsaw

Section

CASUISTIC PAPERS

License

Copyright (c) 2014 Medical Journal of the Rzeszow University and the National Medicines Institute, Warsaw

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