Fibromatosis-like spindle-cell metaplastic carcinoma of the breast – a case report
DOI:
https://doi.org/10.15584/ejcem.2021.1.15Keywords:
breast cancer, fibromatosis, metaplastic breast carcinomaAbstract
Introduction. Metaplastic breast carcinoma is expressing epithelial and/or mesenchymal tissue within the same tumor.
Aim. The aim of this study is to evaluate metaplastic breast carcinoma in a case report and literature review.
Description of the case. The presented case desribes metaplastic carcinoma of the breast in 65 years old female patient.
Conclusion. Fibromatosis-cell metaplastic carcinoma of the breast presents a particularly large diagnostic challenge. Malignant variants of this disease have been described in the literature.
Downloads
References
Benson R, Madan R, Julka PK, Rath GK. Metaplastic carcinoma of breast: A case series of seven patients from a tertiary care center and review of literature. Gulf J Oncolog. 2016;1(21):74-76.
Podetta M, D'Ambrosio G, Ferrari A, et al. Low-grade fibromatosis-like spindle cell metaplastic carcinoma: a basal-like tumor with a favorable clinical outcome. Report of two cases. Tumori. 2009;95(2):264-267.
Nonnis R, Paliogiannis P, Giangrande D, Marras V, Trignano M. Low-grade fibromatosis-like spindle cell metaplastic carcinoma of the breast: a case report and literature review. Clin Breast Cancer. 2012;12(2):147-150.
Gobbi H, Simpson JF, Borowsky A, Jensen RA, Page DL. Metaplastic breast tumors with a dominant fibromatosis-like phenotype have a high risk of local recurrence. Cancer 1999;85(10):2170-2182.
Lee AH. Recent developments in the histological diagnosis of spindle cell carcinoma, fibromatosis and phyllodes tumour of the breast. Histopathology. 2008;52(1):45-57.
Luini A, Aguilar M, Gatti G, et al. Metaplastic carcinoma of the breast, an unusual disease with worse prognosis: the experience of the European Institute of Oncology and review of the literature. Breast Cancer Res Treat. 2007;101(3):349-353.
Rekhi B, Shet TM, Badwe RA, Chinoy RF. Fibromatosis-like carcinoma-an unusual phenotype of a metaplastic breast tumor associated with a micropapilloma. World J Surg Oncol. 2007;5:24.
Dwyer JB, Clark BZ. Low-grade fibromatosis-like spindle cell carcinoma of the breast. Arch Pathol Lab Med. 2015;139(4):552-557.
Tse GM, Tan PH, Lui PC, Putti TC. Spindle cell lesions of the breast-the pathologic differential diagnosis. Breast Cancer Res Treat. 2008;109(2):199-207.
Brogi E. Benign and malignant spindle cell lesions of the breast. Semin Diagn Pathol. 2004;21(1):57-64.
Jones M, Fletcher J. Malignant adenomyoepithelioma of the breast. Pathology. 2017;49(3):322-325.
Tse GM, Tan PH, Putti TC, et al. Metaplastic carcinoma of the breast: a clinicopathological review. J Clin Pathol. 2006;59(10):1079-1083.
Ren W, Guan W, Zhang J, Wang F, Xu G. Pyridoxine 5'-phosphate oxidase is correlated with human breast invasive ductal carcinoma development. Aging (Albany NY). 2019;11(7):2151-2176.
Rakha EA, Badve S, Eusebi V, et al. Breast lesions of uncertain malignant nature and limited metastatic potential: proposals to improve their recognition and clinical management. Histopathology. 2016;68(1):45-56.
Sneige N, Yaziji H, Mandavilli SR, et al. Low-grade (fibromatosis-like) spindle cell carcinoma of the breast. Am J Surg Pathol. 2001;25(8):1009-1016.
Mikudova V, Rejlekova K, Gyarfas J, et al. Leptomeningeal Metastasis in a Breast Cancer Treated with Two Lines of Intrathecal Chemotherapy ‒ a Case Report. Klin Onkol. 2019;32(2):139-142.
Kala C, Athar M, Kala S, et al. Clinical and Cyto-Morphological Characterization of Triple Negative Breast Cancer. J Cytol. 2019;36(2):84-88.
Ye C, Wang W, Xia G, et al. A novel curcumin derivative CL-6 exerts antitumor effect in human gastric cancer cells by inducing apoptosis through Hippo-YAP signaling pathway. Onco Targets Ther. 2019;12:2259-2269.
Chen J, Chen J, He F, et al. Design of a Targeted Sequencing Assay to Detect Rare Mutations in Circulating Tumor DNA. Genet Test Mol Biomarkers. 2019;23(4):264-269.
Soltanian S, Mohamadi N, Rajaei P, Khodami M, Mohammadi M. Phytochemical composition, and cytotoxic, antioxidant, and antibacterial activity of the essential oil and methanol extract of Semenovia suffruticosa. Avicenna J Phytomed. 2019;9(2):143-152.
Miyamoto K, Minegaki T, Tanahashi M, et al. Synergistic Effects of Olaparib and DNA-damaging Agents in Oesophageal Squamous Cell Carcinoma Cell Lines. Anticancer Res. 2019;39(4):1813-1820.
Ge ZC, Qu X, Yu HF, et al. Effect of death decoy receptor 3 on prognosis of breast cancer and function of breast cancer cells in vitro. Zhonghua Yi Xue Za Zhi. 2019;99(14):1081-1085.
Jeleń M, Pluta K, Latocha M, et al. Evaluation of angularly condensed diquinothiazines as potential anticancer agents. Bioorg Chem. 2019;87:810-820.
Yates JR, Mines MJ, Subramanian PS, et al. Periocular Histiocytoid Carcinoma: Potential Diagnostic Challenges. Ocul Oncol Pathol. 2019;5(2):94-101.
Chen Y, Quan R, Bhandari A, et al. Low metallothionein 1M (MT1M) is associated with thyroid cancer cell lines progression. Am J Transl Res. 2019;11(3):1760-1770
Zhang Y, Lin P, Zou JY, et al. MiR-216a-5p act as a tumor suppressor, regulating the cell proliferation and metastasis by targeting PAK2 in breast cancer. Eur Rev Med Pharmacol Sci. 2019;23(6):2469-2475.
Li PW, Wang HY, Xu LL. Effect of TCF21 on proliferation, migration and vascular production of breast cancer cells. Zhonghua Bing Li Xue Za Zhi. 2019;48(4):307-31.
Qian X, Zhang Q, Shao N, et al. Respiratory hyperoxia reverses immunosuppression by regulating myeloid-derived suppressor cells and PD-L1 expression in a triple-negative breast cancer mouse model. Am J Cancer Res. 2019;9(3):529-545.
Parvin T, Das C, Choudhury M, Chattopadhyay BK, Mukhopadhyay M. Prognostic Utility of Cyclin D1 in Invasive Breast Carcinoma. Indian J Surg Oncol. 2019;10(1):167-173.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2021 European Journal of Clinical and Experimental Medicine
This work is licensed under a Creative Commons Attribution 4.0 International License.
Our open access policy is in accordance with the Budapest Open Access Initiative (BOAI) definition: this means that articles have free availability on the public Internet, permitting any users to read, download, copy, distribute, print, search, or link to the full texts of these articles, crawl them for indexing, pass them as data to software, or use them for any other lawful purpose, without financial, legal, or technical barriers other than those inseparable from having access to the Internet itself.
All articles are published with free open access under the CC-BY Creative Commons attribution license (the current version is CC-BY, version 4.0). If you submit your paper for publication by the Eur J Clin Exp Med, you agree to have the CC-BY license applied to your work. Under this Open Access license, you, as the author, agree that anyone may download and read the paper for free. In addition, the article may be reused and quoted provided that the original published version is cited. This facilitates freedom in re-use and also ensures that Eur J Clin Exp Med content can be mined without barriers for the research needs.
